Neural computational accounts of reward-learning have been dominated by the hypothesis that dopamine neurons behave like a reward-prediction error and thus facilitate reinforcement-learning in striatal target neurons. While this framework is consistent with a lot of behavioral and neural evidence, this theory fails to account for a number of behavioral and neurobiological observations. In …
Complex brain functions involve interactions between different brain regions and it is believed that alterations in these network connections may be involved in neurological disorders. In this review written by M.M. Shafi, M.B. Westover, M.D. Fox and A. Pascual-Leone, the authors address how the combination of neuroimaging with noninvasive brain stimulation can be used to …
Featured article of EJN issue 35-5: The Unfolded Protein Response in Models of Human Mutant G93A Amyotrophic Lateral Sclerosis T. Prell1 , J. Lautenschläger1 , O.W. Witte1 , M.T. Carri2,3, J. Grosskreutz1 1 Hans-Berger Department of Neurology, Friedrich-Schiller-University Hospital Jena, Erlanger Allee 101, D-07747 Jena, Germany 2Department of Biology, University of Rome “Tor Vergata”, …