Category Archive: Featured

Patients with Obstructive Sleep Apnea show altered motor cortical plasticity in response to cTBS

Featured Article of EJN Issue 37-11   Motor cortex plasticity induced by theta burst stimulation is impaired in patients with obstructive sleep apnoea  by George M. Opie, Peter G. Catcheside, Zafar A. Usmani, Michael C. Ridding and John G. Semmler Obstructive sleep apnoea (OSA) causes changes within the brain that may affect intracortical inhibition (ICI) …

Continue reading »

High-fat diet acutely affects circadian organization and eating behavior

EJN Article published as part of issue 37/8 by Julie S. Pendergast, Katrina L. Branecky, William Yang, Kate L. J. Ellacott, Kevin D. Niswender and Shin Yamazaki In this EJN article, the effects of 1 week of high-fat diet consumption on tissue and behavioral circadian rhythms in mice were investigated. To determine if the high-fat diet …

Continue reading »

Featured Article – Stimulation of sleep slow oscillations improves the ability of learning new information

    Using EEG, low-frequency, high-amplitude oscillations are characteristic of non-rapid eye movement sleep (NREM). These oscillations have been proposed to play a role in memory. In the featured article entitled “Napping to renew learning capacity: enhanced encoding after stimulation of sleep slow oscillations“, the authors found that stimulation of sleep slow oscillations by transcranial …

Continue reading »

Superior colliculus inactivation alters the relationship between covert visual attention and microsaccades

EJN Article published as part of issue 37/7 by Ziad M. Hafed, Lee P. Lovejoy and Richard J. Krauzlis While microsaccadic eye movements have traditionally been viewed as random, it was recently discovered that their directions can be significantly biased by covertly attended visual stimuli. Using reversible, focal inactivation, we found that activity in the …

Continue reading »

Technical Spotlight – Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo

    Technical Spotlight of EJN issue 37-8 by Ji-Yoen Kim, Ryan T. Ash, Carolina Ceballos-Diaz, Yona Levites, Todd E. Golde, Stelios M. Smirnakis and Joanna L. Jankowsky Freehand injection of recombinant AAV into the neonatal mouse brain offers a fast and easy way to attain widespread genetic manipulation of neurons throughout the brain. Rapid …

Continue reading »

Interview: Rethinking the Sequence of Cellular Events Leading to Alzheimer’s Disease

Neurons can last a lifetime, so how do these cells cope with repetitive stress exposure? In a previous study published in EJN (Doehner, 2012), Knuesel’s Lab investigated the ultrastructural properties of Reelin-positive granular aggregates (typical feature of aging) and found accumulation of Reelin in varicosities in dendritic and axonal compartments, particularly in aged immune-challenged mice. …

Continue reading »

Featured Article – Separate amygdala subregions signal surprise and predictiveness during associative fear learning in humans

  Featured article of EJN issue 37-5 by Sabrina Boll, Matthias Gamer, Sebastian Gluth, Jürgen Finsterbusch and Christian Büchel  We employed an aversive Pavlovian reversal-learning task to investigate computational signals derived from a Rescorla-Wagner/ Pearce-Hall hybrid model of reinforcement learning. Our data show that activity in the corticomedial amygdala as well as in the midbrain …

Continue reading »

Featured Article – Adolescent gain in positive valence of a socially relevant stimulus: engagement of the mesocorticolimbic reward circuitry

ejn12058-toc-0001-m

  Featured article of EJN issue 37-3 by Margaret R. Bell, Kayla C. De Lorme, Rayson J. Figueira, Deborah A. Kashy and Cheryl L. Sisk       Adolescence is a time of major behavioral change, and responses to social cues must mature to promote adult-like behaviors. Juvenile hamsters do not show sexual behavior with …

Continue reading »

Technical Spotlight – Using kinematic analysis of movement to predict the time occurrence of an evoked potential associated with a motor command

  Technical Spotlight of EJN issue 37-2 by Christian O’Reilly, Réjean Plamondon, Mohamed K. Landou and Brigitte Stemmer This article presents an exploratory study investigating the possibility of predicting the time occurrence of a motor event related potential (ERP) from a kinematic analysis of human movements. Although the response-locked motor potential may link the ERP …

Continue reading »

Featured Article – Neuronal responses to face-like stimuli in the monkey pulvinar

  Featured article of EJN issue 37-1 by Minh Nui Nguyen, Etsuro Hori, Jumpei Matsumoto, Anh Hai Tran, Taketoshi Ono and Hisao Nishijo   The pulvinar nuclei appear to function as the subcortical visual pathway that bypasses the striate cortex, rapidly processing coarse facial information. We investigated responses from monkey pulvinar neurons during a delayed …

Continue reading »

Older posts «