There is a vast (and rapidly growing) amount of experimental and clinical data of the nervous system at very diverse spatial scales of activity (e.g. from sub-cellular through to whole organ), with many neurological disorders characterised by oscillations in neural activity across these disparate scales. Computer modelling and the development of associated mathematical theories provide us …
On the occasion of the 2012 FENS Forum of Neuroscience, in this Special Issue, the Editors asked authors to write manuscripts that may represent a somewhat atypical mixture of a position paper and a review, focusing on the potential strength and impact of research strategies in neuroscience focusing on ontogenetic mechanisms, models & early …
Enjoy watching the interview of the Associate Editor, Patricia Gaspar A new Special Feature of EJN focused on the development and plasticity of thalamocortical systems has now been published online. To access the articles of the Special Feature, please click here. In February 2011, scientists assembled in Arolla, a picturesque village in …
Click here to enjoy watching the interview series on the topic This Special Issue of EJN entitled “Beyond Simple Reinforcement Learning: the Computational Neurobiology of Reward-Learning and Valuation” (edited by John O’Doherty) was published online on April 4, 2012 (EJN issue 35-7). Neural computational accounts of reward-learning have been dominated …
What are the precise molecular and cellular mechanisms that the human brain exploits to encode consciousness, identity and thought? This remains undoubtedly one of the greatest scientific challenges facing mankind. This Special Issue addresses with eminent precision the rules that dictate the structural and functional diversity of neurons as well as the molecular principles that …
Guest Editors: L. Bonfanti and G Zupanc Despite the considerable enthusiasm for research on adult neurogenesis, there are a strikingly low number of comparative studies in this field. However knowledge from comparative studies may provide clues about the biological function of adult neurogenesis, which remains largely elusive in the intact mammalian brain. This Special Issue …
One of the most important functions of the brain is to guide our behavior through an ever-changing environment. Circuitries executing and modulating saccadic eye movements represent an elegant model system for investigating how sensory information and goal-related information interact to control and coordinate behavior.
The (re-)discovery that new neurons are generated in the adult mammalian brain has opened new perspectives on the regenerative capacity of the central nervous system, fueling hopes of rapid development of neuronal replacement therapies. This Special Issue of EJN encompasses a wide spectrum of views and opinions by leaders in the field, allowing any interested …
Guest Editors: Vincent Prévot This Special Issue presents current views on the mechanisms of neuronal, glial, and hormonal plasticity in the vertebrate hypothalamus and pituitary, focusing on ontogenic development and reversible changes during circadian, reproductive, and seasonal rhythms. These reviews outline fundamental principles of brain adaptation to constraints of the environment and of the “milieu …
Guest Editor:Didier Pinault This Special Feature of EJN presents ten reviews by world experts conducting basic and clinical research on Deep Brain Stimulation (DBS) to address the mechanisms of action of DBS underlying its effects on the brain and its therapeutic potential for chronic neurological and psychiatric diseases. Read more…